Brainsustain™
is a dietary supplement developed through more than 15 years of research in
the clinical neurosciences by board certified neurologist, David Perlmutter,
MD. Its unique formula enhances brain performance and promotes brain health
by improving the energy production of brain mitochondria, facilitating neural
communication, and providing antioxidant action that reduces the production
and damaging effects of excess free radicals in the brain. This antioxidant
action is vital because excess free radicals are associated with brain inflammation
– a marker and common thread among such neurodegenerative disorders as
Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and
ALS. Brainsustain™’s key ingredients have been extensively studied
for efficacy at some of the world’s most wellrespected medical institutions.
Ingredients include:
Coenzyme Q-10 measurably increases the efficiency of cellular energy production,
as demonstrated in studies performed at the Massachusetts General Hospital.(1)
In addition, it serves as a potent brain antioxidant. These effects explain
why major institutions worldwide are vigorously evaluating coenzyme Q10 as a
therapeutic aid in brain disorders.
Alpha Lipoic Acid provides powerful antioxidant action and regenerates other
important brain antioxidants including vitamins E, C, and glutathione. Unlike
other antioxidants, alpha lipoic acid is both fat- and water-soluble, greatly
enhancing its ability to be absorbed from the gut and penetrate into the brain.(2)
N-Acetyl-L-Cysteine (NAC) dramatically increases the body’s production
of glutathione, one of the brain’s most important antioxidants. NAC itself
is a potent antioxidant shown to reduce formation of nitric oxide, a free radical
implicated for a causative role in Parkinson’s disease, Alzheimer’s
disease, and other neurodegenerative disorders.(3)
Acetyl-L-Carnitine, like coenzyme Q-10, enhances neuronal energy pro-duction
by transporting fuel sources into the mitochondria – the energy producing
machinery of the neuron. This particularly benefits damaged brain neurons, which
are characterized by decreased energy producing ability. In addition, acetyl-L-carnitine
acts as an effective antioxidant and been demon-strated to protect laboratory
animals from developing parkinsonism when they are exposed to chemicals known
to induce the condition.(4) A report in a recent issue of Neurology found that
acetyl-L-carnitine profoundly reduces the rate of progression of Alzheimer’s
disease in younger patients.(5)
Vitamin E exhibits profound ability to limit free radical damage in the brain
– the likely explanation of why it outperformed a highly touted “Alzheimer’s
drug” in clinical trials reported in the New England Journal of Medicine.(6)
Diets rich in Vitamin E have been shown to reduce the risk of Parkinson’s
disease by an incredible 61%,(7) and to dramatically slow disease progression
in already-diagnosed patients when supplemented with Vitamin C.(8)
Gingko biloba, one of the most extensively studied nutritional supplements for
neurodegenerative conditions, directly improves brain metabolism, increases
brain blood flow, and provides antioxidant action. In a placebo-controlled,
double-blind randomized trial published in the Journal of the American Medical
Association, Gingko biloba not only stabilized Alzheimer’s disease; many
subjects demonstrated an actual improvement noted in various standardized psychological
tests.(9)
Vitamin D may have even greater ability to quench brain free radicals than Vitamin
E, several studies indicate. Deficiencies of Vitamin D have been found in cases
of Parkinson’s, Alzheimer’s, and MS.(10)
Vitamin B12 (Methylcobalamin) is critical for maintaining myelin, the protective
coat surrounding each neuron. As with Vitamin D, Vitamin B12 deficiency is associated
with neurodegenerative conditions.
Phosphatidylserine produces marked memory and learning improvements in demented
patients, according to research conducted at Stanford University.(11) Like acetyl-L-carnitine
and coenzyme Q-10, phosphatidylserine plays an important role in neuronal energy
production and chemical communication.