FEES INCLUDE: Kit: Genova Diagnostics $14.95, Great Smokies Performance of Test: $83.00, Dr Banks follow-up consultation: $125 (email/phone) Recurrent or chronic vaginitis is one of the most common reasons that women seek medical attention. Although vaginitis may be caused by a foreign organism, such as N. gonorrhea, far more cases arise from alterations in the vaginal milieu that trigger inflammation. Factors influencing the vaginal environment include pH, glycogen and glucose, sex hormones, immune health, the natural flushing action of vaginal secretions, and the level of protective Lactobacilli. Other predisposing factors include diabetes mellitus, sexual contact, and oral contraceptives. Identifying these factors is essential in preventing recurrence of infection. Just as important is the identification of the causative organisms, in order to develop the most effective treatment. Genova Diagnostics' Vaginosis Profile is one of the most comprehensive evaluations available. This assessment includes microscopic examination of vaginal fluid, gram stain, and cultures for bacteria and yeast. Bacterial cultures demonstrate the presence of possible pathogens, as well as the concentration of Lactobacillus, the protective bacteria that is easily eradicated by oral antibiotics. Although Staphylococcus aureus and Group B beta Streptococcus are the only recognized aerobes of concern (the latter in the case of pregnancy), other aerobic organisms have been observed to contribute to vaginosis symptoms, particularly when Lactobacillus levels are low. For this reason, all organisms are cultured and reported. A sensitivity panel accompanies every culture, so that the clinician who desires to treat the organism can select the most appropriate agents. A comprehensive microscopic exam can help determine the cause of an imbalance. Each sample is assessed for the following: . Presence of cell lysis - from Lactobacillus overgrowth which causes excess acidity . Clue cells - suggesting Gardnerella, the most common cause of vaginitis . White blood cells - to determine the degree of inflammation and identify allergic vaginitis . Trichomonas - to identify parasitic infection . Yeast morphology - which identifies both budding and hyphenated forms of yeast The Vaginosis profile from Genova Disgnostics also features the Nugent Scoring System to help identify or rule out Gardnerella vaginatis. By identifying and grading the types of organisms present, the Nugent Scoring System can also predict relapse in susceptible individuals, and determine who may need repeat analysis. |